What is the name of the combination of DNA with histones?

The combination of DNA with histones is known as chromatin. Chromatin is a complex of DNA and protein found in the nucleus of eukaryotic cells. Its primary role is to package DNA into a more compact structure, which helps in organizing DNA during cell division and regulating gene expression. Chromatin can exist in two forms: euchromatin, which is less tightly packed and active in transcription, and heterochromatin, which is more tightly packed and generally inactive.

Nucleosomes, while closely related, refer specifically to the unit structure formed when DNA wraps around a core of histone proteins. Each nucleosome consists of about 146 base pairs of DNA wrapped around a set of eight histone proteins.

Chromosomes represent the higher-order structures formed when chromatin fibers condense further during cell division. The genome refers to the complete set of genetic material in an organism, which includes all chromosomes and their associated chromatin.

Thus, the correct identification of the mixture of DNA and histones as chromatin underscores its fundamental role in organizing and regulating access to genetic information within the cell.